Recently I came across a few articles about 3D printing of
organs and tissues.
Sample articles:
The greatest success so far has been achieved by scientists
from Tel Aviv University. They were the first to print an exact replica of the
heart with blood vessels and chambers. The heart was printed from human cells
and specific biological materials (substances consisting of sugars and
proteins). The printed heart has the size of a rabbit's heart. His cells may
shrink, but they must learn to pump so that they can cooperate.
On the other hand, researchers from the University of
Nagasaki and Saga are studying the method of printing 3D structures without
scaffolding to create tissues for transplantation. Methods using scaffolds are
widely known in medicine, but problems such as immunogenicity, scaffold
degradation, and immune response may occur. Treatments based on scaffolding are
also limited by materials that can be used to create scaffoldings. Thanks to
the MCS (multicellular spheroids) method, in which the cells have the
possibility of joining one another individually, the scientists were able to
create the structures of esophageal tissue and then transplant them in rats.
After surgery, none of the rats showed any complications.
Biomaterials used in 3D printing of organs should have the
same biochemical, mechanical and topographic properties as the patient's own
tissues. By using biomaterials from patients, scientists eliminate the risk of
implant rejection. This is extremely important because about 50% of transplants
are rejected within 10-12 years of transplantation.
3D printing in biomedicine creates great opportunities.
Thanks to it, the waiting time for transplant can be shortened many times and
the percentage of transplants rejected by the organism may be lowered.
1. What other organs or implants can be obtained by 3D
printing method?
2. In the next 10-20 years, do you think that 3D bioprinters
will be present in most hospitals, and most patients will have access to
printed organs?
3. What technology could potentially replace the 3D printing
of organs or be available faster?
4. Do you see any other advantages or disadvantages of the
ability to implant 3D printed organs?